The poisoning of fluoroquinolone is caused by antibiotics. It can trigger extreme side effects, such as nausea vomiting, diarrhea, muscle pain, depression, and psychosis. Floxing is a different name for this condition.
Avoiding fluoroquinolones is a good idea when patients have experienced dangerous side effects with an antibiotic with a fluoroquinolone or quinolone previously. Patients over 65 with kidney disease or who have received an organ transplant should be given special consideration.
Fluoroquinolones comprise the majority of the quinolone antibiotics being used. They have the element fluorine within their chemical structure. They are effective against Gram-negative as well and Gram-positive bacteria.
Fluoroquinolones kill bacteria through blocking enzymes that typically untangle DNA during cell reproduction. These enzymes usually cut DNA’s doublehelix. They then pass another strand of DNA through the gap, and then fix the cut.
However, quinolones are able to bind to enzymes, stopping them from mending their cuts. Fluorine atoms were added into the quinolones’ structures in the late 1980s. This allowed antibiotics to penetrate all tissues of the body and even the central nerve system. This also enhanced their effectiveness against a vast variety of bacterial diseases.
Fluoroquinolones may be of benefit in cases where other antibiotics fail to provide sufficient efficacy.
However, they’re over-used like many antibiotics. Serious side effects have been caused by them over time, and a number of warnings from FDA limit their use. Many label modifications have been needed, and some fluoroquinolones have warnings in black boxes.
What antibiotics are considered fluoroquinolones, and which aren’t?
The medications listed comprise Cipro gemifloxacin [Factive] Cipro, ciprofloxacin levofloxacin (“Levaquin”) Levaquin), levofloxacin (“Levaquin”) and moxifloxacin (“Avelox”) norfloxacin („NoroxinNoroxin), and ofloxacin (“Floxin”Floxin).
What is the fluoroquinolone toxicity syndrome?
The signs and symptoms
There have been some serious adverse reactions linked to fluoroquinolones, including long-term and permanent disabilities. Ciprotoxicity symptoms can also include:
– Damage to mitochondrial DNA and mitochondrial dysfunction
– Brain fog
– Peripheral Neuropathy
– Blurry Vision
– DNA Damage
– Gaba and Gut Damage can cause anxiety/depression.
– Tendonitis
– Muscle Atrophy
– Reflexes that are more than
The pain of low back, tendonitis and tendon rupture are among the initial signs of Ciprotoxicity. Fluoroquinolones could increase the risk for peripheral neuropathy by 47% over time.
Ciprofloxacin is proven to inhibit normal maintenance and transcription of mitochondrial DNA through altering the topology of mitochondrial DNA. Tenocytes are damaged by mitochondria during fluoroquinolone treatment may cause tendinitis and tendon rupture. It could also lead to inflammation or fatigue.
For more information, click floxed treatment
